Fenugreek - Get the Facts on Herbal Supplements

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Fenugreek site:.gov

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  • The first recorded use of fenugreek is described on an ancient Egyptian papyrus dated to 1500 B.C. Fenugreek seed is commonly used in cooking.<a href="#hdng0">(More...)</a>

  • Results were discussed in the context of control of endosperm galactomannan hydrolysis by the cotyledons of fenugreek embryo.<a href="#hdng1">(More...)</a>



<a name="hdng0"></a>The first recorded use of fenugreek is described on an ancient Egyptian papyrus dated to 1500 B.C. Fenugreek seed is commonly used in cooking. <a href="http://nccam.nih.gov/health/fenugreek/" TARGET="_blank" [1]</a> Fenugreek can cause irritation when applied to the skin. Given its historical use for inducing childbirth, women should use caution when taking fenugreek during pregnancy.<a href="http://nccam.nih.gov/health/fenugreek/" TARGET="_blank" [1]</a> There is not enough scientific evidence to support the use of fenugreek for any other health condition.<a href="http://nccam.nih.gov/health/fenugreek/" TARGET="_blank" [1]</a>

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<a name="hdng1"></a>Results were discussed in the context of control of endosperm galactomannan hydrolysis by the cotyledons of fenugreek embryo. <a href="http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1062688" TARGET="_blank" [2]</a> The detergent-solubilized GMGT from the developing fenugreek seed endosperm catalyzes the transfer of Gal residues from UDP-Gal to (1→4)-β-linked manno-oligosaccharides with chain lengths comprising five or more Man residues.<a href="http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=166532" TARGET="_blank" [3]</a> Independently of whether or not GMGT action is single chain, the model predicts that fenugreek GMGT is capable of catalyzing the transfer of a Gal residue to an acceptor Man residue adjacent to one already carrying a substituent.<a href="http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=166532" TARGET="_blank" [3]</a>

When the labeled polysaccharide products are hydrolyzed using the A. niger endo-β-mannanase, the labeled oligosaccharide fragments always include M5G2 (structure in Table I) in which the two Gal substituents are adjacent (data not shown; similar data from expressed, soluble fenugreek GMGT illustrated in Edwards et al., 1999 ; Fig. 4 ).<a href="http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=166532" TARGET="_blank" [3]</a>

In Figure 4, it is assumed that the six-site mannan chain recognition sequence deduced for the detergent-solubilized fenugreek GMGT (Fig. 3 ) is valid also in the membrane-bound state.<a href="http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=166532" TARGET="_blank" [3]</a>

Figure 4 A model for the interaction of MS and GMGT during galactomannan biosynthesis in fenugreek.<a href="http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=166532" TARGET="_blank" [3]</a> Reid JSG, Bewley JD. A dual role for the endosperm and its galactomannan reserves in the germinative physiology of fenugreek ( Trigonella foenum-graecum L.), an endospermic leguminous seed.<a href="http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=166532" TARGET="_blank" [3]</a> Galactomannan biosynthesis is catalyzed in vitro by membrane preparations isolated from the developing endosperms of fenugreek ( Trigonella foenum-graecum ; Man/Gal ratio in vivo 1.1), guar (Man/Gal ratio 1.6), and senna ( Senna occidentalis ; Man/Gal ratio 3.3).<a href="http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=166532" TARGET="_blank" [3]</a>

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1. <a href="http://nccam.nih.gov/health/fenugreek/" TARGET="_blank">Fenugreek [NCCAM Herbs at a Glance]</a>
<a href="http://nccam.nih.gov/health/fenugreek/" TARGET="_blank">http://nccam.nih.gov/health/fenugreek/</a>

2. <a href="http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1062688" TARGET="_blank">d-Galactose Uptake by Fenugreek Cotyledons</a>
<a href="http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1062688" TARGET="_blank">http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1062688</a>

3. <a href="http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=166532" TARGET="_blank">Transfer Specificity of Detergent-Solubilized Fenugreek Galactomannan Galactosyltransferase</a>
<a href="http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=166532" TARGET="_blank">http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=166532</a>

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